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Penicillin allergy and antibiotics — GPhC CRA MCQ

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ModerateInfectionsPenicillin allergy and antibioticsGPhC CRA

A woman presents a prescription for phenoxymethylpenicillin for tonsillitis. Her PMR records previous anaphylaxis after amoxicillin with facial swelling and wheeze. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Query the prescription and discuss a non-penicillin alternative

Anaphylaxis to amoxicillin suggests serious beta-lactam allergy risk. Phenoxymethylpenicillin is another penicillin and should not be supplied without prescriber review. Antihistamine pre-treatment does not make the prescription safe.

Reference: BNF; NICE CKS