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DOAC renal monitoring — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentDOAC renal monitoringGPhC CRA

A 79-year-old woman takes apixaban for atrial fibrillation. Her GP asks the pharmacy what routine monitoring is relevant because she has CKD stage 3. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Renal function, full blood count and liver function at appropriate intervals

DOACs do not require INR dose titration, but renal and hepatic function and full blood count are monitored for safety and dosing. Reduced renal function increases bleeding risk and may affect dosing. The monitoring interval depends on renal function and patient factors.

Reference: BNF