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NSAIDs in CKD — GPhC CRA MCQ

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EasyRenal and Hepatic ImpairmentNSAIDs in CKDGPhC CRA

A 68-year-old man with CKD stage 4 asks for diclofenac tablets for shoulder pain. He also takes losartan. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DAdvise against oral diclofenac and refer for safer pain management

NSAIDs can worsen renal function and increase hyperkalaemia risk, especially with RAAS blockers. CKD stage 4 makes oral NSAIDs particularly concerning. Safer alternatives and assessment are appropriate.

Reference: BNF; NICE CKS