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Methotrexate infection counselling — GPhC CRA MCQ

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ModeratePatient CounsellingMethotrexate infection counsellingGPhC CRA

A patient taking methotrexate asks whether a fever and mouth ulcers should wait until the next routine rheumatology appointment. What would you advise the patient?

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Correct answer: ASeek urgent advice because infection or blood dyscrasia may be serious

Fever, mouth ulcers, sore throat, bruising or breathlessness can indicate methotrexate toxicity or serious infection. Urgent advice and blood tests may be needed. Folic acid does not make warning symptoms safe to ignore.

Reference: BNF