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GLP-1 receptor agonist pancreatitis warning — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsGLP-1 receptor agonist pancreatitis warningGPhC CRA

A 52-year-old woman starts semaglutide for type 2 diabetes. She asks which symptoms should prompt urgent medical advice. What would you advise the patient?

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Correct answer: B — Severe persistent abdominal pain with or without vomiting

GLP-1 receptor agonists can be associated with pancreatitis, although it is uncommon. Severe persistent abdominal pain, especially with vomiting, requires urgent assessment. Common gastrointestinal effects should still be distinguished from red-flag symptoms.

Reference: BNF; MHRA Drug Safety Update