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Amlodipine ankle oedema — GPhC CRA MCQ

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EasyCardiovascular TherapeuticsAmlodipine ankle oedemaGPhC CRA

A 70-year-old woman collects amlodipine 10 mg daily. She reports bilateral ankle swelling since the dose was increased, with no breathlessness or calf pain. Her BP is now controlled. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: AExplain that ankle oedema is a recognised effect and refer to the prescriber for review

Dose-related peripheral oedema is a common adverse effect of dihydropyridine calcium-channel blockers. The pharmacist should assess for red flags and refer for dose reduction or switching if troublesome. Diuretics are usually not helpful for CCB-related oedema and abrupt stopping without review may destabilise blood pressure.

Reference: BNF