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Mesalazine monitoring — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsMesalazine monitoringGPhC CRA

A 43-year-old woman starts mesalazine modified-release tablets for ulcerative colitis. She asks why blood and urine checks are arranged. What monitoring is required?

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Correct answer: D — Renal function monitoring is required because mesalazine can affect the kidneys

Mesalazine can rarely cause renal impairment, so renal function monitoring is recommended. Patients should also report unexplained bleeding, bruising or sore throat depending on product advice. Drug levels are not routinely monitored in community practice.

Reference: BNF