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Gabapentin renal dose — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentGabapentin renal doseGPhC CRA

A 76-year-old woman with eGFR 24 mL/min/1.73 m² is prescribed gabapentin 300 mg three times daily for neuropathic pain. She has not used it before. What is the most appropriate action?

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Correct answer: B — Query the starting dose because gabapentin requires renal dose adjustment

Gabapentin is renally cleared and dose adjustment is required in renal impairment. Starting too high increases dizziness, sedation and falls risk. The prescription should be checked before supply.

Reference: BNF