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Flucloxacillin administration — GPhC CRA MCQ

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EasyInfectionsFlucloxacillin administrationGPhC CRA

A patient is prescribed flucloxacillin 500 mg four times daily for cellulitis. He usually eats frequent snacks and asks when to take it. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Take on an empty stomach, at least 30–60 minutes before food where practical

Flucloxacillin absorption is reduced by food, so it is usually taken on an empty stomach. Patients should still prioritise completing the prescribed regimen and seeking help if cellulitis worsens. Dose spacing should be practical and safe.

Reference: BNF