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NSAID renal risk — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsNSAID renal riskGPhC CRA

A 78-year-old man taking ramipril and furosemide asks to buy ibuprofen for back pain. His last eGFR was 38 mL/min/1.73 m². What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: EAvoid oral ibuprofen and discuss safer analgesia or prescriber review

ACE inhibitor or ARB, diuretic and NSAID combinations increase acute kidney injury risk, especially in older adults with CKD. Safer analgesia should be considered and the prescriber contacted if pain is significant. Stopping prescribed medicines without review is unsafe.

Reference: BNF; NICE CKS