skip to main content

Opioid constipation prophylaxis — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

EasyCNS TherapeuticsOpioid constipation prophylaxisGPhC CRA

A 69-year-old man starts morphine modified-release for cancer pain. He has no regular bowel medicine and reports previous constipation with codeine. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Recommend a regular stimulant laxative with or without a softener/osmotic laxative

Opioid-induced constipation is common and tolerance does not reliably develop. Regular laxative prophylaxis is usually appropriate when starting strong opioids. Loperamide would worsen constipation.

Reference: BNF; NICE CKS