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Verapamil and beta-blocker — GPhC CRA MCQ

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HardDrug InteractionsVerapamil and beta-blockerGPhC CRA

A man taking bisoprolol 5 mg daily presents a new prescription for verapamil modified-release for angina. His pulse is 54 bpm. What is the most important interaction to flag?

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Correct answer: CFlag additive bradycardia and heart block risk

Verapamil and beta-blockers have additive negative effects on heart rate and atrioventricular conduction. Bradycardia at baseline increases concern. The prescription should be clarified before supply.

Reference: BNF