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SSRI early counselling — GPhC CRA MCQ

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EasyCNS TherapeuticsSSRI early counsellingGPhC CRA

A 28-year-old woman starts sertraline 50 mg daily for depression. She asks when it will work and whether she can stop if she feels nauseated after the first few doses. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Explain that benefit may take a few weeks and early nausea often settles

SSRIs often take several weeks to show antidepressant benefit and early gastrointestinal effects can settle. Patients should be warned about initial anxiety, sleep changes and the need to seek help if suicidal thoughts worsen. St John’s wort and alcohol can increase risks.

Reference: BNF; NICE CKS