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Ondansetron constipation and QT risk — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsOndansetron constipation and QT riskGPhC CRA

A patient prescribed ondansetron after chemotherapy asks about side effects. He also takes amiodarone and has a history of constipation. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Counsel on constipation and flag possible QT-prolongation risk with amiodarone

Ondansetron commonly causes constipation and can prolong the QT interval. Concomitant QT-prolonging medicines such as amiodarone increase clinical concern. The pharmacist should check local guidance and refer if risk is significant.

Reference: BNF