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DOAC renal dosing check — GPhC CRA MCQ

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HardCardiovascular TherapeuticsDOAC renal dosing checkGPhC CRA

A 82-year-old woman presents a prescription for dabigatran for atrial fibrillation. Her shared record shows eGFR 28 mL/min/1.73 m² and she weighs 49 kg. She has not taken dabigatran before. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Query the prescription because renal function may make dabigatran unsuitable

Renal function is critical for DOAC selection and dosing, especially for dabigatran, which is substantially renally cleared. Reduced renal function and low body weight increase bleeding risk, so the prescription should be checked before supply. DOACs still require renal function review and safety monitoring.

Reference: BNF