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Anticholinergic burden falls — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and SafetyAnticholinergic burden fallsGPhC CRA

A 79-year-old woman taking amitriptyline, oxybutynin and chlorphenamine reports dry mouth, constipation and two recent falls. Her daughter asks if this is ageing. What is the most appropriate action?

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Correct answer: C — Review medicines for anticholinergic burden and refer to the prescriber

Multiple anticholinergic medicines can cause dry mouth, constipation, cognitive impairment, urinary retention and falls. Older adults are particularly vulnerable. Deprescribing or alternatives should be reviewed with the prescriber.

Reference: BNF; NICE CKS