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Levothyroxine administration — GPhC CRA MCQ

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EasyEndocrine TherapeuticsLevothyroxine administrationGPhC CRA

A 48-year-old woman taking levothyroxine 100 micrograms daily has variable TSH results. She takes it with breakfast, ferrous sulfate and calcium carbonate. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Take levothyroxine on an empty stomach and separate from iron and calcium

Iron and calcium can reduce levothyroxine absorption, and food can also affect consistency. Levothyroxine is usually taken on an empty stomach with separation from interacting medicines. Consistent administration helps interpretation of thyroid function tests.

Reference: BNF; NICE CKS