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Oral prednisolone course counselling — GPhC CRA MCQ

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HardRespiratory TherapeuticsOral prednisolone course counsellingGPhC CRA

A patient taking warfarin begins regular miconazole oral gel for oral candidiasis. What is the safest action?

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Correct answer: B — Arrange urgent review of the interacting treatment

Miconazole oral gel can be systemically absorbed and strongly inhibit warfarin metabolism, producing dangerous INR elevation and bleeding. The combination should be avoided or managed only with an agreed specialist monitoring plan. Dose separation does not prevent a metabolic interaction.

Reference: https://www.gov.uk/drug-safety-update/miconazole-including-oral-gel-reminder-of-potential-for-serious-interactions-with-warfarin