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NSAID gastroprotection — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsNSAID gastroprotectionGPhC CRA

A 76-year-old woman is prescribed naproxen 500 mg twice daily for osteoarthritis. She has a history of peptic ulcer disease and takes aspirin 75 mg daily. What is the most appropriate action?

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Correct answer: D — Query gastroprotection and bleeding risk with the prescriber

Age, previous ulcer and aspirin increase NSAID-related gastrointestinal bleeding risk. Gastroprotection and the need for NSAID therapy should be reviewed. Stopping aspirin without prescriber advice may increase cardiovascular risk.

Reference: BNF; NICE CKS