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Citalopram and QT-prolonging medicines — GPhC CRA MCQ

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ModerateDrug InteractionsCitalopram and QT-prolonging medicinesGPhC CRA

A 69-year-old woman taking citalopram 20 mg daily is prescribed erythromycin. She has a history of syncope and low potassium after diuretics. What is the most important interaction to flag?

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Correct answer: A — Flag additive QT-prolongation risk

Citalopram and erythromycin can both prolong the QT interval. Older age, syncope history and electrolyte disturbance increase risk. Alternative therapy or monitoring should be considered.

Reference: BNF