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Sodium valproate pregnancy prevention — GPhC CRA MCQ

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HardCNS TherapeuticsSodium valproate pregnancy preventionGPhC CRA

A 25-year-old woman of childbearing potential collects sodium valproate for epilepsy. She says she is not using contraception and has not seen a specialist for over a year. What is the legal classification/requirement?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Do not treat as routine supply; refer urgently for specialist review and pregnancy prevention requirements

Valproate has major teratogenic and neurodevelopmental risks and is subject to strict pregnancy prevention requirements. A pharmacist should ensure the patient is aware and referred for urgent specialist review rather than routine continuation without safeguards. Abrupt cessation can also be dangerous, so specialist input is essential.

Reference: MHRA Drug Safety Update; BNF