skip to main content

SGLT2 inhibitor sick day advice — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

EasyEndocrine TherapeuticsSGLT2 inhibitor sick day adviceGPhC CRA

A 64-year-old woman taking dapagliflozin for type 2 diabetes has vomiting and reduced food intake. She asks whether to continue her tablets while unwell. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Temporarily withhold dapagliflozin and seek advice if ketone symptoms or dehydration occur

SGLT2 inhibitors can increase risk of diabetic ketoacidosis, including euglycaemic DKA, during acute illness, dehydration or reduced intake. Sick-day advice commonly includes temporary withholding and seeking help if unwell. Insulin should not be stopped without specialist advice.

Reference: MHRA Drug Safety Update; BNF