skip to main content

Pregabalin dependence and tapering — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateCNS TherapeuticsPregabalin dependence and taperingGPhC CRA

A 44-year-old woman taking pregabalin 150 mg twice daily for neuropathic pain says she wants to stop because of dizziness. She asks whether she can stop tonight. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Advise discussing a gradual reduction with the prescriber

Pregabalin can cause dizziness and may cause withdrawal symptoms if stopped abruptly, especially after regular use. A gradual reduction is usually advised. It also has dependence and misuse potential, so safe use and review are important.

Reference: BNF; MHRA Drug Safety Update