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Levothyroxine and calcium — GPhC CRA MCQ

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EasyDrug InteractionsLevothyroxine and calciumGPhC CRA

A woman taking levothyroxine starts calcium carbonate for osteoporosis prevention. She takes all morning medicines together with tea. What is the most important interaction to flag?

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Correct answer: E — Calcium can reduce levothyroxine absorption, so doses should be separated

Calcium salts can bind levothyroxine and reduce absorption, causing unstable thyroid control. Administration should be separated and taken consistently. Other interacting products include iron and some antacids.

Reference: BNF