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Nitrofurantoin renal impairment — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentNitrofurantoin renal impairmentGPhC CRA

A woman with cystitis presents a prescription for nitrofurantoin. Her summary care record shows eGFR 28 mL/min/1.73 m2 last week. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Do not supply until renal suitability and antibiotic choice are reviewed

Nitrofurantoin efficacy and safety depend on renal function. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF