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Digoxin and amiodarone — GPhC CRA MCQ

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ModerateDrug InteractionsDigoxin and amiodaroneGPhC CRA

A patient on digoxin is newly prescribed amiodarone after an arrhythmia clinic appointment. They report nausea and blurred vision. What is the most important interaction to flag?

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Correct answer: E — Increased digoxin concentration and toxicity risk

Amiodarone can increase digoxin exposure and toxicity. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF