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Missed DOAC doses in AF — GPhC CRA MCQ

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EasyCardiovascular TherapeuticsMissed DOAC doses in AFGPhC CRA

A 69-year-old woman taking apixaban 5 mg twice daily for atrial fibrillation says she has missed several doses this week. She has no bleeding and asks whether she can take extra tablets today. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DAdvise her not to take extra doses and to re-establish the regular twice-daily schedule

Extra doses increase bleeding risk and do not safely compensate for missed anticoagulation. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; NICE CKS