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Clopidogrel gastroprotection — GPhC CRA MCQ

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ModerateGastrointestinal TherapeuticsClopidogrel gastroprotectionGPhC CRA

A patient on clopidogrel needs gastroprotection after a previous ulcer bleed. The GP asks for a PPI choice. What is the most appropriate alternative?

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Correct answer: C — Lansoprazole or pantoprazole after prescriber assessment

Some PPIs are preferred over omeprazole when clopidogrel interaction is a concern. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; NICE CKS