Methotrexate monitoring — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsMethotrexate monitoringGPhC CRA

A patient on methotrexate asks why the GP checks bloods before issuing repeats. They feel well. What monitoring is required?

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Reveal the answer and explanation

Correct answer: A — Full blood count, liver function and renal function according to schedule

Methotrexate can cause bone marrow suppression, hepatotoxicity and renal-related toxicity. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; NICE CKS