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Spironolactone monitoring — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsSpironolactone monitoringGPhC CRA

A woman with heart failure is prescribed spironolactone in addition to ramipril. She asks why repeat blood tests have been arranged. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Serum potassium and renal function after starting and during dose changes

Combining spironolactone with an ACE inhibitor increases hyperkalaemia and renal impairment risk. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; NICE CKS