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Methotrexate weekly dosing — GPhC CRA MCQ

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ModeratePatient Counselling and Pharmaceutical CareMethotrexate weekly dosingGPhC CRA

A patient receives methotrexate 2.5 mg tablets and asks why the box says weekly when most tablets are daily. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: C — Take the exact weekly dose on the same day each week and avoid extra doses

Methotrexate dosing errors can be serious or fatal. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; MEP; NICE CKS