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Theophylline toxicity symptoms — GPhC CRA MCQ

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HardRespiratory TherapeuticsTheophylline toxicity symptomsGPhC CRA

A patient taking theophylline modified-release tablets reports nausea, palpitations and tremor after starting erythromycin. They ask to buy an antacid. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: DWithhold supply advice and contact the prescriber urgently

Theophylline has a narrow therapeutic index and interacting macrolides can precipitate toxicity. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; NICE CKS; BTS/NICE/SIGN asthma guideline