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Analgesia in liver disease — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentAnalgesia in liver diseaseGPhC CRA

A patient with stable chronic liver disease asks for pain relief and has been taking high-dose paracetamol for several days. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Reduce to a safer regimen and refer for clinical advice on maximum dosing

Paracetamol dosing requires caution in liver disease and overdose risk must be avoided. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF