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Warfarin and fluconazole — GPhC CRA MCQ

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HardDrug InteractionsWarfarin and fluconazoleGPhC CRA

A patient stable on warfarin is prescribed fluconazole for oral candidiasis. They ask whether INR checks need changing. What is the most important interaction to flag?

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Correct answer: A — Raised INR and bleeding risk

Fluconazole can increase warfarin effect and bleeding risk. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF