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Domperidone and clarithromycin — GPhC CRA MCQ

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ModerateDrug InteractionsDomperidone and clarithromycinGPhC CRA

A patient prescribed clarithromycin asks to use leftover domperidone for nausea. They have a history of prolonged QT interval. What is the most important interaction to flag?

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Correct answer: B — QT prolongation and arrhythmia risk

Both medicines can increase QT-related cardiac risk. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF