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NSAID gastroprotection — GPhC CRA MCQ

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HardMusculoskeletal TherapeuticsNSAID gastroprotectionGPhC CRA

A patient with osteoarthritis and previous peptic ulcer takes low-dose aspirin and is newly prescribed long-term naproxen without gastroprotection. What is the best prescription-screening action?

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Correct answer: D — Reassess the need for oral naproxen and co-prescribe gastroprotection if it is retained

Option D applies NICE: oral NSAID use requires individual gastrointestinal, renal, hepatic, cardiovascular and medicine-risk assessment, and gastroprotection should be offered when it is used. Option A relies on symptom review instead of reducing baseline ulcer risk. Option E adds diclofenac cardiovascular risk and still omits gastroprotection. Option B introduces opioid harms without first reviewing the analgesic plan. Option C removes prescribed antiplatelet prevention without authority.

Reference: NICE NG226: https://www.nice.org.uk/guidance/NG226/chapter/recommendations