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Neuropathic pain — GPhC CRA MCQ

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ModerateCNS TherapeuticsNeuropathic painGPhC CRA

A patient with diabetic neuropathic pain has inadequate relief from paracetamol and cannot tolerate amitriptyline due to antimuscarinic effects. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Duloxetine after prescriber assessment

Duloxetine is an option for painful diabetic neuropathy when suitable. The best answer addresses the key safety, legal or pharmaceutical care issue in the vignette. The other options would either delay appropriate care, create a new risk, or fail to resolve the issue. This is consistent with the cited UK reference for safe pharmacy practice.

Reference: BNF; NICE CKS