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Carbimazole agranulocytosis — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsCarbimazole agranulocytosisGPhC CRA

A patient has started carbimazole for hyperthyroidism. Two weeks later they ask what symptoms should prompt urgent contact. They have no symptoms today and are collecting a repeat supply. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Sore throat, fever or mouth ulcers

Carbimazole can rarely cause agranulocytosis. Patients should be counselled to seek urgent medical advice if they develop sore throat, fever, mouth ulcers or other infection signs. This counselling is important even when baseline blood tests are normal.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment