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DMARD monitoring — GPhC CRA MCQ

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ModerateMusculoskeletal TherapeuticsDMARD monitoringGPhC CRA

A patient taking sulfasalazine for rheumatoid arthritis asks why the GP keeps requesting blood tests. He is clinically well but has recently had his dose increased. What monitoring is required?

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Correct answer: E — Full blood count and liver function monitoring

Sulfasalazine can cause blood dyscrasias and hepatotoxicity, particularly around initiation and dose changes. Full blood count and liver function monitoring are therefore important. Lithium, INR and digoxin monitoring relate to other medicines and conditions. Symptom absence does not remove the need for routine safety monitoring.

Reference: BNF; NICE CKS