skip to main content

PPI step-down — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardGastrointestinal TherapeuticsPPI step-downGPhC CRA

A 49-year-old patient has taken omeprazole 20mg daily for uncomplicated reflux for 18 months. Symptoms are controlled and there is no ulcer bleeding, Barrett's oesophagus or chronic NSAID use. They ask if they need to continue indefinitely. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Discuss step-down or review with the prescriber

Long-term PPI therapy should be reviewed and continued where there is an ongoing indication. In uncomplicated controlled reflux, dose reduction, intermittent use or review may be appropriate. Increasing dose without indication adds adverse-effect and interaction burden.

Reference: NICE CKS; BNF