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Clozapine infection warning — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyClozapine infection warningGPhC CRA

A patient taking clozapine asks for advice about fever and sore throat. He feels unwell and says his next routine blood test is in ten days. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Refer urgently for same-day blood count assessment

Clozapine can cause neutropenia and agranulocytosis. Fever and sore throat in a patient taking clozapine require urgent assessment and blood count checking. Waiting for routine monitoring could delay detection of a serious adverse effect. Dose changes should be guided by the specialist service.

Reference: BNF; clozapine monitoring requirements