skip to main content

ACE inhibitor angioedema — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardAdverse Drug Reactions and Drug SafetyACE inhibitor angioedemaGPhC CRA

A patient taking ramipril develops sudden lip swelling and hoarseness. He arrives at the pharmacy asking for an antihistamine. He has no visible rash. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Arrange urgent emergency assessment for possible angioedema

ACE inhibitors can cause angioedema, which may threaten the airway and can occur without urticaria. Lip swelling with hoarseness requires urgent emergency assessment. Antihistamines may not be adequate and should not delay referral. Continuing ramipril without review would be unsafe.

Reference: BNF; NICE CKS