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Antipsychotic metabolic monitoring — GPhC CRA MCQ

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ModerateCNS TherapeuticsAntipsychotic metabolic monitoringGPhC CRA

A 39-year-old patient starts olanzapine for schizophrenia. The community mental health team asks the GP practice to arrange physical health monitoring. The patient has gained weight on previous antipsychotic therapy. What monitoring is required?

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Correct answer: D — Weight, glucose or HbA1c, lipids and blood pressure

Olanzapine is associated with weight gain, dyslipidaemia and glucose dysregulation. Baseline and follow-up cardiometabolic monitoring is needed. The other tests are not routine safety checks for olanzapine therapy.

Reference: BNF; NICE CKS