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Beta-blocker in asthma — GPhC CRA MCQ

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HardRespiratory TherapeuticsBeta-blocker in asthmaGPhC CRA

A patient with asthma controlled on inhaled corticosteroid/formoterol is prescribed propranolol 40mg twice daily for tremor. They ask whether it is safe because their friend had breathing problems with beta-blockers. What is the most important interaction to flag?

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Correct answer: D — Propranolol may provoke bronchospasm and reduce beta-agonist effect

Non-selective beta-blockers such as propranolol can worsen bronchospasm and antagonise beta-2 agonists. The prescription should be queried and a safer alternative considered if treatment is needed. The other options are not the clinically important interaction.

Reference: BNF