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Opioid constipation — GPhC CRA MCQ

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EasyCNS TherapeuticsOpioid constipationGPhC CRA

A 62-year-old patient starts morphine MR for cancer pain and immediate-release morphine for breakthrough pain. No laxative is included. They ask whether constipation is likely. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — A regular stimulant laxative should usually be considered

Constipation is a predictable opioid adverse effect and tolerance does not reliably develop. A regular laxative is commonly required when starting strong opioids. Loperamide and reduced fluid intake would worsen constipation.

Reference: BNF; NICE CKS