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Clozapine infection warning — GPhC CRA MCQ

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EasyCNS TherapeuticsClozapine infection warningGPhC CRA

A patient taking clozapine phones the pharmacy with a sore throat, fever and mouth ulcers. Their next clozapine supply is due tomorrow. They ask whether to wait for their routine blood test next week. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Seek urgent blood count advice through the clozapine monitoring service

Clozapine can cause neutropenia and agranulocytosis. Fever, sore throat or mouth ulcers require urgent assessment and blood count advice through the monitoring system. Delaying until the routine test could miss a serious blood dyscrasia.

Reference: BNF; Clozapine monitoring service guidance