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Heparin-induced thrombocytopenia — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyHeparin-induced thrombocytopeniaGPhC CRA

A hospital discharge prescription includes dalteparin after surgery. The discharge summary mentions previous heparin-induced thrombocytopenia. The patient asks whether the injection is safe. What monitoring is required?

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Correct answer: D — Immediate prescriber review because heparin re-exposure may be unsafe

A history of heparin-induced thrombocytopenia is clinically significant and may make heparin or low molecular weight heparin re-exposure unsafe. The pharmacist should query the prescription urgently before supply. Platelet monitoring and anticoagulant choice require specialist input. Prophylactic dosing does not remove the concern.

Reference: BNF; MEP