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Digoxin and verapamil — GPhC CRA MCQ

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ModerateDrug InteractionsDigoxin and verapamilGPhC CRA

An older patient taking digoxin for atrial fibrillation is newly prescribed verapamil for rate control. She reports occasional nausea and blurred vision. What is the most important interaction to flag?

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Correct answer: AVerapamil can increase digoxin concentration

Verapamil can increase digoxin concentrations and both drugs can slow atrioventricular conduction. Symptoms such as nausea and visual disturbance may suggest digoxin toxicity and require assessment. The pharmacist should query the prescription and ensure monitoring is considered. The interaction is not total loss of absorption.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-39