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Montelukast neuropsychiatric effects — GPhC CRA MCQ

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HardRespiratory TherapeuticsMontelukast neuropsychiatric effectsGPhC CRA

A parent collects montelukast 5mg chewable tablets for a child with asthma. The child has a history of anxiety and the parent asks what adverse effects to watch for. Inhaled therapy is continued. What monitoring is required?

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Correct answer: E — Report mood, sleep or behaviour changes promptly

Montelukast has been associated with neuropsychiatric adverse reactions, including sleep disturbance and mood or behaviour changes. Families should be counselled to report concerning symptoms promptly. It is not a replacement for inhaled corticosteroid therapy or an acute reliever.

Reference: BNF; MHRA Drug Safety Update