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Peripheral oedema with amlodipine — GPhC CRA MCQ

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EasyCardiovascular TherapeuticsPeripheral oedema with amlodipineGPhC CRA

A 63-year-old patient started amlodipine 5mg once daily 3 weeks ago. They report new bilateral ankle swelling, worse in the evening, but no breathlessness or chest pain. Their BP is improved. What is the most appropriate alternative?

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Correct answer: D — Discuss dose adjustment or alternative with the prescriber

Ankle oedema is a recognised adverse effect of dihydropyridine calcium-channel blockers. Management usually involves dose review or a change in therapy rather than self-treatment with a diuretic. Breathlessness or unilateral swelling would require more urgent assessment for other causes.

Reference: BNF; NICE CKS